On May 28, 2012, Turkish Airlines inaugurated flights to Bilbao (Spain) and Leipzig (Germany). The flights are operated with Airbus A319 aircraft, 4 times a week, according to the following schedule:
| Istanbul - Bilbao | Departure Arrival |
| Monday, Tuesday, Thursday, Saturday | 09: 40 / 12: 50 (TK1317) |
| Bilbao to Istanbul | Departure Arrival |
| Monday, Tuesday, Thursday, Saturday | 13: 50 / 18: 45 (TK1318) |
| Istanbul - Leipzig | Departure Arrival |
| Monday, Wednesday, Friday, Sunday | 11: 55 / 13: 50 (TK1337) |
| Leipzig and Istanbul | Departure Arrival |
| Monday, Wednesday, Friday, Sunday | 14: 45 / 18: 40 (TK1338) |